The family Agamidae is a large and diverse assemblage of Old World lizards. Though similar to the New World's Iguanidae. Agamids all have acrodont teeth, meaning the teeth sit on the crests of the jawbones. Most agamids also have two pair of enlarged, fang-like teeth at the front of each jawbone. Most agamids reproduce by laying eggs. All species have four well-developed limbs and five digits on each foot (except the genus Sitana, which only has four toes on each foot).

The skull contains postorbital and squamosal arches. Osteoderms are absent. The tail, if lost, cannot be regenerated. 

The oddest and most diverse body types for lizards are arguably found among agamids. These include flying dragons, frilled lizards, chameleon dragons and earless bark lizards.

Range: Africa (not Madagascar), Asia, Europe, Australia, and Indo-Australia. Absent from New Zealand and most Pacific Islands east of New Guinea.